Comparison of the Effect of 2% Ginger Mouthwash and Nystatin Mouthwash on Denture Stomatitis

Denture stomatitis is the chronic inflammation of mucus along with the presence and activity of Candida albicans. Ginger, which is a herb with antibacterial and antifungal proportion, has shown proven effects against Candida albicans. In this study the effects of ginger mouthwashes and nystatin mouthwashes on the treatment of denture stomatitis have been compared. This study was conducted in a doubled_ blind clinical trial on 50 patients with denture stomatitis. Given consent, the patients were categorized into two groups and one group was given the ginger mouthwash and another one was given the nystatin mouthwash for two weeks. At the end of the first and second week the erythematous zone was examined and its type of denture stomatitis was specified. Furthermore, in the first session and the end of the treatment sample were taken from the palate with in order to carry out microbial culture and colony count. The data was analyzed by SPSS 21 and the results were compared with Chisquare test. During the two-week treatment, both treatments resulted in the recovery of denture stomatitis significantly. However, the mentioned treatments did not have any clinically significant differences. No significant difference in the reduction of the number of colonies was seen between the two groups. Moreover, the level of the patient's satisfaction with the two treatments was similar. Considering the similar effectiveness of ginger and nystatin in the treatment of denture stomatitis and also patients similar satisfaction with both mouthwashes, the ginger mouthwashes can be an alternative treatment for nystatin.